Modernising aseptic compounding through the use of new technology: a validation and proof of concept study

Abstract Introduction There is an urgent need to reform care pathways keep patients, wherever possible, outside of hospital and in turn freeing up capacity addressing the elective backlog crisis. To address such issues futureproof its services, NHS modernising approach care. Within aseptic space, current transformation plans1 require provision large-scale quantities injectable medicines leveraging new technologies enable large scale roll out services as outpatient antimicrobial therapy (OPAT). Aim CIVAS@IP5 Wales' first National Pharmacy Technical Services Unit has recently invested state-of-the-art technology, which transforming compounding, making it possible significantly facilitate creation local OPAT services. The technology question Gri-fill®4 2, a semi-automated system for compounding hazardous non-hazardous sterile preparations. aim this study, UK use Gri-fill®4, was report on suitability Methods Due nature, pilot study required no ethical approval patients were involved nor any patient data collected. Over course number weeks, validation measurements carried Gri-fill®4. This included time motion assessments manual pathway compared using Results revealed that preparation infusion bag achieved within average 2.64 minutes. represents substantial 80% saving when approximately 13 Furthermore, batch 46 infusions completed with 50% fewer critical manipulations (92 versus 184 pathway), reducing potential error whilst also requiring verifications by staff. Once scaled, increase productivity will have significant real-world benefits are reliant responsive provisions. On top improvements, introduction afforded sustainability improvements; less plastic consumables production each batch. Discussion/Conclusion It important note our reports impact only one unit. As there obvious scalability findings but limitations regard logistics practicalities compounding; both these be explored. In conclusion, units can drastically improved through modernisation technology. extent improvement discusses implications future References 1. P., C., Transforming pharmacy England: national Department Health Social Care Lord Carter Coles. 2020. 2. Grifols. Gri-fill 4 Semi-automatic Compounding Device. 2019. Available from: https://www.grifolsinclusiv.com/documents/90075605/0/inclusiv+Gri-fill+4+Brochure/ae8ce6e8-d2e0-49e0-b76f-8121539db44a